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Disorders of puberty

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2013Embargo end date: 17 Nov 2017 United Kingdom English Publisher:Elsevier BVJournal:Medicine, volume 49, pages 583-586 (issn: 1357-3039,

Authors: Hendriks, AEJ; Prentice, P; Williams, R;

doi: 10.1016/j.mpmed.2021.06.012 , 10.1016/j.mpmed.2013.07.006 , 10.1016/j.mpmed.2017.06.011 , 10.17863/cam.15569

Disorders of puberty

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Abstract

Puberty is the process of development of adult secondary sexual characteristics. Disorders of puberty can be classified into early (precocious) and late (delayed) puberty. Early (precocious) puberty can be secondary to either activation of the hypothalamic-pituitary-gonadal axis (gonadotrophin-dependent, or central) or altered regulation of sex hormone production in the gonads, adrenals or other tissues (gonadotrophin-independent or peripheral). Delayed puberty is most often constitutional, but hypogonadotrophic (central) and hypergonadotrophic (peripheral) hypogonadism should be considered. In this article, we discuss the clinical and biochemical features of normal and abnormal puberty.

Country

United Kingdom

Related Organizations

University of Cambridge
United Kingdom

Keywords

puberty, hypogonadism, constitutional delay of growth and puberty, MRCP, gonadotrophins, precocious puberty, premature adrenarche

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	2
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average