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Calcium channel blockers

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2003 English Publisher:Elsevier BVJournal:Medicine, volume 40, pages 112-114 (issn: 1357-3039, Copyright policy )
Authors: Buckley, Nicholas; Dawson, Andrew; Whyte, Ian M;

doi: 10.1016/j.mpmed.2011.12.022 , 10.1016/j.mpmed.2015.12.029 , 10.1016/j.mpmed.2007.08.025 , 10.1383/medc.31.10.37.27821

handle: 1959.13/1322252 , 1885/26988

Calcium channel blockers

Abstract

Overdose of calcium channel blockers is potentially lethal. Verapamil and diltiazem are much more dangerous than dihydropyridines. Hypotension with (verapamil and diltiazem) or without (dihydropyridines) heart block and bradycardia are the most important features. Routine management usually comprises intravenous fluids, activated charcoal, whole-bowel irrigation (for modified-release products) and prolonged electrocardiographic monitoring. Antidotes for cardiac effects include calcium, bicarbonate, high-dose insulin–euglycaemia and vasopressors with atropine and/or transvenous pacing in cases of symptomatic bradycardia.

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Keywords

calcium channel blockers, calcium, atropine, cardiotoxicity, bicarbonate, amlodipine, benzothiazepine derivative, poisoning, calcium chann antidotes, Keywords: 1,4 dihydro 2,6 dimethyl 5 nitro 4 [2 (trifluoromethyl)phenyl] 3 pyridinecarboxylic acid methyl ester, activated carbon, antidotes, adrenergic receptor stimulating agent, antidote

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    popularity
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
29
Top 10%
Top 10%
Average
Green
gold
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