On the trail of empty MHC class-I
Copyright policy )On the trail of empty MHC class-I
Since being proposed nearly 25 years ago that MHC-I molecules free of peptide ligand possess a conformation that is distinct from that of the mature loaded form, considerable research has been conducted in order to isolate and characterise such a species. While some progress has been made in our understanding, many questions still surround the nature and loading of empty MHC-I. However, the necessary tools to address these questions may finally be at hand.
- Monash University Australia
Antigen Presentation, Mice, Protein Conformation, Histocompatibility Antigens Class I, Animals, Humans, CD8-Positive T-Lymphocytes, Peptide Fragments
Antigen Presentation, Mice, Protein Conformation, Histocompatibility Antigens Class I, Animals, Humans, CD8-Positive T-Lymphocytes, Peptide Fragments
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).8 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!