
pmid: 23062612
Complement may play a dual role in cancer: it may contribute either to the development or to the inhibition of tumour growth. Its components may be candidate biomarkers facilitating the disease detection, its progress or effectiveness of therapy. Additionally, complement deficiencies may increase the risk of infections and contribute to the higher mortality, especially in patients undergoing aggressive chemotherapy. In this paper, possible cancer associations of one of the factors activating complement via the lectin pathway, mannan-binding lectin (MBL), are discussed.
Neoplasms, Animals, Humans, Complement Pathway, Mannose-Binding Lectin, Protein Multimerization, Medical Oncology, Mannose-Binding Lectin, Models, Biological
Neoplasms, Animals, Humans, Complement Pathway, Mannose-Binding Lectin, Protein Multimerization, Medical Oncology, Mannose-Binding Lectin, Models, Biological
| citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 22 | |
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
