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Molecular Cell
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Molecular Cell
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Molecular Cell
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Molecular Toggle Switch of Histone Demethylase LSD1

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2015 English Publisher:Elsevier BVJournal:Molecular Cell, volume 57, pages 949-950 (issn: 1097-2765, Copyright policy )
Authors: Shin, Jaehoon; Ming, Guo-li; Song, Hongjun;

doi: 10.1016/j.molcel.2015.03.007

pmid: 25794611

pmc: PMC5476831

Molecular Toggle Switch of Histone Demethylase LSD1

Abstract

In this issue of Molecular Cell, Laurent et al. (2015) demonstrated that a neuron-enriched isoform of LSD1 (LSD1+8a) within a SVIL-containing complex exhibits H3K9me1/2-specific demethylation activity. Such activity was crucial for gene activation during mammalian neurogenesis.

Related Organizations
Keywords

Histone Demethylases, Neurons, Microfilament Proteins, Humans, Membrane Proteins, Cell Biology, Molecular Biology

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    popularity
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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
15
Top 10%
Average
Top 10%
hybrid