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Micro(RNA) Managing by mTORC1

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2015 United States English Publisher:Elsevier BVJournal:Molecular Cell, volume 57, pages 575-576 (issn: 1097-2765, Copyright policy )
Authors: Jewell, Jenna L; Flores, Fabian; Guan, Kun-Liang;

doi: 10.1016/j.molcel.2015.02.006

pmid: 25699705

pmc: PMC4378617

Micro(RNA) Managing by mTORC1

Abstract

In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.

Country
United States
Related Organizations
Keywords

Ribonuclease III, Biomedical and clinical sciences, TOR Serine-Threonine Kinases, Health sciences, Proto-Oncogene Proteins c-mdm2, Cell Biology, Biological Sciences, Mechanistic Target of Rapamycin Complex 1, Medical and Health Sciences, Biological sciences, MicroRNAs, Multiprotein Complexes, Animals, Humans, Biochemistry and Cell Biology, Generic health relevance, Molecular Biology, Developmental Biology

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 7
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Average
Average
Green
hybrid