Name: Please Keep Me 2uned to PKM2
Creator: McKnight, Steven L.
Keywords: Thyroid Hormones, Membrane Proteins, Cell Biology, Ribonucleotides, Aminoimidazole Carboxamide, 3. Good health, Gene Expression Regulation, Neoplastic, Animals, Humans, Carrier Proteins

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2014 English Publisher:Elsevier BVJournal:Molecular Cell, volume 53, pages 683-684 (issn: 1097-2765,

Authors: McKnight, Steven L.;

doi: 10.1016/j.molcel.2014.02.022

pmid: 24606916

Please Keep Me 2uned to PKM2

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Abstract

In this issue of Molecular Cell, Keller et al. (2014) found that binding of the metabolite SAICAR to PKM2 induces the protein kinase activity of an enzyme normally designed to terminate the glycolytic pathway.

Related Organizations

The University of Texas Southwestern Medical Center
United States

Keywords

Thyroid Hormones, Membrane Proteins, Cell Biology, Ribonucleotides, Aminoimidazole Carboxamide, Gene Expression Regulation, Neoplastic, Animals, Humans, Carrier Proteins, Molecular Biology, Protein Kinase Inhibitors, Signal Transduction, Thyroid Hormone-Binding Proteins

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