Box H/ACA Small Ribonucleoproteins
Copyright policy )Box H/ACA Small Ribonucleoproteins
Box H/ACA RNAs represent an abundant, evolutionarily conserved class of small noncoding RNAs. All H/ACA RNAs associate with a common set of proteins, and they function as ribonucleoprotein (RNP) enzymes mainly in the site-specific pseudouridylation of ribosomal RNAs (rRNAs) and small nuclear RNAs (snRNAs). Some H/ACA RNPs function in the nucleolytic processing of precursor rRNA (pre-rRNA) and synthesis of telomeric DNA. Thus, H/ACA RNPs are essential for three fundamental cellular processes: protein synthesis, mRNA splicing, and maintenance of genome integrity. Recently, great progress has been made toward understanding of the biogenesis, intracellular trafficking, structure, and function of H/ACA RNPs.
- Paul Sabatier University France
- Paul Sabatier University France
- Hungarian Academy of Sciences Hungary
Models, Molecular, RNA, Untranslated, Protein Conformation, Archaeal Proteins, RNA Splicing, Active Transport, Cell Nucleus, Coiled Bodies, Cell Biology, Ribonucleoproteins, Small Nuclear, Genomic Instability, Evolution, Molecular, RNA, Ribosomal, Protein Biosynthesis, Animals, Humans, Nucleic Acid Conformation, RNA, Messenger, RNA Processing, Post-Transcriptional, Molecular Biology, Intramolecular Transferases, Telomerase, Pseudouridine
Models, Molecular, RNA, Untranslated, Protein Conformation, Archaeal Proteins, RNA Splicing, Active Transport, Cell Nucleus, Coiled Bodies, Cell Biology, Ribonucleoproteins, Small Nuclear, Genomic Instability, Evolution, Molecular, RNA, Ribosomal, Protein Biosynthesis, Animals, Humans, Nucleic Acid Conformation, RNA, Messenger, RNA Processing, Post-Transcriptional, Molecular Biology, Intramolecular Transferases, Telomerase, Pseudouridine
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