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A Bitter PP1 Fights the Sweet Polo

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2008 United States English Publisher:Elsevier BVJournal:Molecular Cell, volume 30, pages 541-542 (issn: 1097-2765, Copyright policy )
Authors: Archambault, Vincent; Chen, Feng; Glover, David M.;

doi: 10.1016/j.molcel.2008.05.012

pmid: 18538650

A Bitter PP1 Fights the Sweet Polo

Abstract

In a recent paper in Developmental Cell, Yamashiro et al. (2008) report that the PP1 regulatory subunit MYPT1 interacts with PLK1 and antagonizes essential mitotic functions of PLK1, at least in part by promoting the dephosphorylation of PLK1 at Thr210.

Country
United States
Related Organizations
Keywords

Mitosis, Cell Cycle Proteins, 612, Cell Biology, Protein Serine-Threonine Kinases, 630, Polo-Like Kinase 1, Protein Phosphatase 1, Proto-Oncogene Proteins, Humans, Phosphorylation, Molecular Biology

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
hybrid