The Making of an siRNA
Copyright policy )The Making of an siRNA
An array of gene silencing pathways share a common early step: Dicer cleaves double-stranded RNA (dsRNA) into approximately 20-25 nucleotide fragments that direct the silencing machinery to specific targets. A recent report in Cell reveals how Dicer's two RNase III domains collaborate during dsRNA processing and sets the stage for a deeper understanding of Dicer's roles in later phases of silencing complex assembly.
- NORTHWESTERN UNIVERSITY United States
- Northwestern University United States
Ribonuclease III, Cell Biology, Protein Biosynthesis, Animals, Humans, RNA-Induced Silencing Complex, RNA Interference, Gene Silencing, RNA, Small Interfering, Molecular Biology, RNA, Double-Stranded
Ribonuclease III, Cell Biology, Protein Biosynthesis, Animals, Humans, RNA-Induced Silencing Complex, RNA Interference, Gene Silencing, RNA, Small Interfering, Molecular Biology, RNA, Double-Stranded
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).4 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!