Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD), characterized by persistent peripheral thrombocytosis and a tendency for thrombosis and hemorrhage.1 Erythromelalgia is a kind of cutaneous manifestation, which appears as a thrombotic complication in patients with myeloproliferative disorders such as essential thrombocythemia and polycythemia vera.2 In a retrospective study of 268 patients with essential thrombocythemia, related cutaneous manifestations were found in 58 (22%) and fifteen patients (26%) had erythromelalgia.3 We describe a case of Essential Thrombocythemia in a young lady who was diagnosed and managed at our hospital.