BK polyomavirus: emerging pathogen
Copyright policy )BK polyomavirus: emerging pathogen
BK polyomavirus (BKPyV) is a small double-stranded DNA virus that is an emerging pathogen in immunocompromised individuals. BKPyV is widespread in the general population, but primarily causes disease when immune suppression leads to reactivation of latent virus. Polyomavirus-associated nephropathy and hemorrhagic cystitis in renal and bone marrow transplant patients, respectively, are the most common diseases associated with BKPyV reactivation and lytic infection. In this review, we discuss the clinical relevance, effects on the host, virus life cycle, and current treatment protocols.
- University of Michigan–Ann Arbor United States
- University of Michigan–Flint United States
Immunocompromised Host, Polyomavirus Infections, Tumor Virus Infections, BK Virus, Humans, Communicable Diseases, Emerging, Kidney Transplantation, Bone Marrow Transplantation
Immunocompromised Host, Polyomavirus Infections, Tumor Virus Infections, BK Virus, Humans, Communicable Diseases, Emerging, Kidney Transplantation, Bone Marrow Transplantation
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