Hantavirus cardiopulmonary syndrome: immune response and pathogenesis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2006 English Publisher:Elsevier BVJournal:Microbes and Infection, volume 8, pages 2,324-2,330 (issn: 1286-4579,

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Authors: Alessandra A, Borges; Gelse M, Campos; Marcos L, Moreli; Ricardo L M, Souza; Victor H, Aquino; Fabiano P, Saggioro; Luiz T M, Figueiredo;

doi: 10.1016/j.micinf.2006.04.019

pmid: 16793309

Hantavirus cardiopulmonary syndrome: immune response and pathogenesis

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Abstract

Hantaviruses are emerging viruses in the Americas that cause cardiopulmonary syndrome with high lethality. The intense cellular immune response to hantavirus alters normal endothelial cell barrier functions and seems to be harmful to the host. On the other hand, the humoral immune response seems to be essential for recovery from infection.

Related Organizations

Universidade de São Paulo
Brazil
UNIVERSIDADE DE SAO PAULO
Brazil

Keywords

Orthohantavirus, Immunity, Cellular, Humans, Viremia, Hantavirus Pulmonary Syndrome, Antibodies, Viral, Models, Biological

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