Immune responses to Puumala virus infection and the pathogenesis of nephropathia epidemica

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2004 English Publisher:Elsevier BVJournal:Microbes and Infection, volume 6, pages 238-245 (issn: 1286-4579,

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Authors: Terajima, Masanori; Vapalahti, Olli; Van Epps, Heather Lin; Vaheri, Antti; Ennis, Francis A.;

doi: 10.1016/j.micinf.2003.10.017

pmid: 15049335

handle: 20.500.14038/32687

Immune responses to Puumala virus infection and the pathogenesis of nephropathia epidemica

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Abstract

Puumala virus, causative agent of a mild form of hemorrhagic fever with renal syndrome, also known as nephropathia epidemica, induces long-lasting humoral and cellular immunity in patients. The virus itself is not cytopathic, and the immune responses to the virus may be involved in teh pathogenesis of the disease.

Related Organizations

University of Massachusetts Medical School
United States
University of Helsinki
Finland
Seattle Institute for Biomedical and Clinical Research
United States

Keywords

570, Hantavirus Infections, Hemorrhagic Fever with Renal Syndrome, Humans, Puumala virus, 630

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