Diastolic Dysfunction and Hypertension
Copyright policy )Diastolic Dysfunction and Hypertension
Left ventricular (LV) diastolic dysfunction (LVDD) is characterized by alterations in LV diastolic filling, and is a strong predictor of cardiovascular events and heart failure. Hypertension is the most important risk factor for LVDD in the community and promotes LVDD through several mechanisms, including hemodynamic overload and myocardial ischemia. Associated factors such as age, ethnicity, dietary sodium, obesity, diabetes mellitus, and chronic kidney disease also contribute to LVDD in hypertensive individuals. Blood pressure lowering using antihypertensive medications can improve LVDD; however, it remains unclear whether this improvement in LV diastolic function can improve cardiovascular outcomes.
- Brigham and Women's Faulkner Hospital United States
- State University of Campinas Brazil
Ventricular Dysfunction, Left, Diastole, Systole, Hypertension, Hemodynamics, Humans, Hypertrophy, Left Ventricular, Prognosis
Ventricular Dysfunction, Left, Diastole, Systole, Hypertension, Hemodynamics, Humans, Hypertrophy, Left Ventricular, Prognosis
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