
pmid: 21616120
Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular and immune systems. Ghrelin and its receptor are expressed in a number of cancers and cancer cell lines and may play a role in processes associated with cancer progression, including cell proliferation, apoptosis, and cell invasion and migration.
proliferation, Prostate-Cancer, Des-Acyl Ghrelin, Inhibits Apoptosis, NSCLC, Models, Biological, cell migration and invasion, Human Pituitary-Tumors, Neoplasms, Paracrine Communication, Hormone Secretagogue Receptor, cancer, Animals, Humans, Endocrine Tumors, non-small cell lung cancer, Activated Protein-Kinase, Cell-Lines, apoptosis, SCLC, growth hormone secretagogue receptor, Ghrelin, Autocrine Communication, In-Vitro, ghrelin, Messenger-Rna Expression, small cell lung cancer
proliferation, Prostate-Cancer, Des-Acyl Ghrelin, Inhibits Apoptosis, NSCLC, Models, Biological, cell migration and invasion, Human Pituitary-Tumors, Neoplasms, Paracrine Communication, Hormone Secretagogue Receptor, cancer, Animals, Humans, Endocrine Tumors, non-small cell lung cancer, Activated Protein-Kinase, Cell-Lines, apoptosis, SCLC, growth hormone secretagogue receptor, Ghrelin, Autocrine Communication, In-Vitro, ghrelin, Messenger-Rna Expression, small cell lung cancer
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