Anti-Müllerian hormone and folliculogenesis

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2005 Netherlands English Publisher:Elsevier BVJournal:Molecular and Cellular Endocrinology, volume 234, pages 81-86 (issn: 0303-7207,

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Authors: Visser, Jenny; Themmen, Axel;

doi: 10.1016/j.mce.2004.09.008

pmid: 15836956

Anti-Müllerian hormone and folliculogenesis

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Abstract

This paper reviews the role of anti-Müllerian hormone, a member of the TGF(beta) family signaling through a BMP-like pathway, in the ovary. In vivo and in vitro studies showed that AMH has an inhibitory effect on primordial follicle recruitment and it decreases the sensitivity of follicles for the FSH-dependent selection for dominance. Besides its functional role in the ovary, AMH serum level serves as an excellent candidate marker of ovarian reserve.

Country

Netherlands

Related Organizations

Erasmus University Medical Center
Netherlands
Erasmus University Rotterdam
Netherlands

Keywords

Anti-Mullerian Hormone, EMC MM-01-39-04, Biological Factors, Mice, Testicular Hormones, Fertility, Ovarian Follicle, Animals, Humans, Female, Follicle Stimulating Hormone, Glycoproteins, Signal Transduction

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