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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Revista del Laborato...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Revista del Laboratorio Clínico
Article . 2014 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Utilidad de la procalcitonina para predecir bacteriemia en pacientes oncológicos con fiebre

Authors: Enrique Jiménez-Santos; Ana Hernando-Holgado; Luis García de Guadiana-Romualdo; Monserrat Viqueira-González; Pablo Cerezuela Fuentes; Ignacio Español Morales;

Utilidad de la procalcitonina para predecir bacteriemia en pacientes oncológicos con fiebre

Abstract

Resumen Introduccion La bacteriemia es una de las principales causas de morbimortalidad en el paciente con cancer. El objetivo de este estudio es evaluar la utilidad de la procalcitonina como marcador predictor de bacteriemia en pacientes oncologicos y oncohematologicos que acudieron al Servicio de Urgencias de nuestro hospital. Material y metodos Se incluyeron en el estudio 152 episodios de fiebre en 134 pacientes adultos oncologicos. Al ingreso en el Servicio de Urgencias una muestra de sangre fue extraida para la medida de proteina C reactiva (PCR) y procalcitonina (PCT). Los episodios febriles se clasificaron en dos grupos en funcion de los resultados del hemocultivo: bacteriemicos (n = 22) y no bacteriemicos (n = 130). El rendimiento diagnostico de los biomarcadores como predictores de bacteriemia fue calculado mediante el analisis del area bajo la curva Receiver Operating Characteristic. Resultados Las concentraciones de PCT y PCR fueron significativamente mas altas en los episodios febriles con bacteriemia que en los no bacteriemicos. La PCT presento un rendimiento diagnostico mas alto que la PCR como predictor de bacteriemia (area bajo la curva Receiver Operating Characteristic: PCT 0,781 (IC 95%: 0,667 - 0,895) vs. PCR: 0,632 (IC 95%: 0,493 - 0,771); p = 0,02). Un punto de corte de 0,20 ng/mL presento un valor predictivo negativo de 95,8% para descartar bacteriemia. Conclusion En el Servicio de Urgencias, la medida de PCT en pacientes oncologicos con fiebre es una herramienta util para descartar bacteriemia y puede contribuir a la toma inicial de decisiones terapeuticas y a racionalizar la solicitud del hemocultivo.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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Cancer Research
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