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Diabetes and the Abdominal Aortic Aneurysm

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2010Publisher:Elsevier BVJournal:Journal of Vascular Surgery, volume 51, page 526 (issn: 0741-5214,

Authors: Saran Shantikumar; D.J.A. Scott; R. Ajjan; K.E. Porter;

doi: 10.1016/j.jvs.2009.12.038 , 10.1016/j.ejvs.2009.10.014

pmid: 19948418

Diabetes and the Abdominal Aortic Aneurysm

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Abstract

The aim of this review is to delineate the association between abdominal aortic aneurysms (AAAs) and diabetes mellitus. Mechanisms for the underlying association are then discussed.A systematic review of the English-language literature using PubMed, EMBASE and Cochrane databases was undertaken up to September 2009. Studies reporting appropriate prevalence data were identified and a meta-analysis performed.Eleven studies were identified. The prevalence of diabetes mellitus in studied patients with AAA ranged from 6% to 14%. The prevalence of diabetes in control patients without AAA ranged from 17% to 36%. Pooled analysis suggested a reduced rate of diabetes amongst people with AAA compared to those without (OR 0.65, 0.60-0.70, p<0.001).Studies so far suggest a protective role for diabetes on the development of AAA. Further research is required to demarcate the underlying mechanisms for this possible association.

Related Organizations

University of Leeds
United Kingdom

Keywords

Medicine(all), Diabetes, Pathogenesis, Diabetes Complications, Diabetes Mellitus, Prevalence, Abdominal aortic aneurysm, Humans, Surgery, Glycaemia, Cardiology and Cardiovascular Medicine, Aortic Aneurysm, Abdominal

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	152
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%