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pmid: 15514608
Sarcoidosis is a clinical entity characterized by noncaseating epithelioid granulomas affecting multiple organs. The cause remains perplexing, but the available evidence points to an exaggerated cellular response as the feature of the disorder. The granulomas, composed of mononuclear phagocytes encircled by CD4 T lymphocytes, have the potential for distorting tissue architecture and thus compromising organ function. Sarcoidosis is a systemic disease, but its symptoms are usually secondary to lung, liver, skin, lymph node, and eye involvement. Clinically manifest cardiac involvement is seen in 5% of patients. It is characterized by conduction anomalies, pericarditis, and congestive heart failure, with the potential for causing sudden death. We report on an unusual case of cardiac sarcoidosis resulting in aortic valve insufficiency and left ventricular outflow tract (LVOT) obstruction.
Pulmonary and Respiratory Medicine, Male, Sarcoidosis, Aortic Valve Insufficiency, Humans, Surgery, Middle Aged, Cardiology and Cardiovascular Medicine, 35, Ventricular Outflow Obstruction
Pulmonary and Respiratory Medicine, Male, Sarcoidosis, Aortic Valve Insufficiency, Humans, Surgery, Middle Aged, Cardiology and Cardiovascular Medicine, 35, Ventricular Outflow Obstruction
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 10 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |