Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study
Copyright policy )Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study
The purpose of this study was to examine the effect of a pulpal revascularization procedure for immature necrotic teeth with apical periodontitis.Twelve patients, each with an immature permanent tooth with chronic or acute apical periodontitis, were recruited. A triantibiotic mix (ciprofloxacin, metronidazole, and minocycline) was used to disinfect the pulp for 1 week. Then a blood clot was created in the canal, over which grey mineral trioxide aggregate was placed. Patients were recalled periodically.Six patients dropped from the study (as a result of pain or failure to induce bleeding after canal disinfection) and instead received a standard apexification procedure. Another 3 patients did not attend any recall appointments. The remaining teeth (n = 3) were found to exhibit complete root development, with a positive response to pulp testing.Revascularization could be effective for managing immature permanent teeth with apical periodontitis with appropriate case selection.
- Stomatology Hospital China (People's Republic of)
- University of Hong Kong China (People's Republic of)
- Peking University China (People's Republic of)
- University of Hong Kong (香港大學) China (People's Republic of)
- Peking University Cancer Hospital China (People's Republic of)
Male, Aluminum Compounds - therapeutic use, Bicuspid - pathology, 610, Tooth Apex - physiopathology, Minocycline, Minocycline - administration & dosage, Root Canal Therapy - methods, Odontogenesis - physiology, Physiologic - physiology, Silicates - therapeutic use, Anti-Infective Agents, Ciprofloxacin, Metronidazole, Calcium Compounds - therapeutic use, Anti-Bacterial Agents - administration & dosage, Dental Pulp Necrosis, Humans, Bicuspid, Aluminum Compounds, Child, Blood Coagulation, Neovascularization, Anti-Infective Agents - administration & dosage, Incisor - pathology, Dental Pulp, Blood Coagulation - physiology, Dental Pulp Necrosis - therapy, Guided Tissue Regeneration, Oxides - therapeutic use, Periapical Periodontitis - therapy, Root Canal Preparation - methods, Calcium Compounds, Root Canal Filling Materials - therapeutic use, Anti-Bacterial Agents, Guided Tissue Regeneration - methods, Incisor, Drug Combinations, Treatment Outcome, Ciprofloxacin - administration & dosage, Neovascularization, Physiologic - physiology, Female, Metronidazole - administration & dosage, Dental Pulp Cavity, Dental Pulp Cavity - blood supply, Dental Pulp - blood supply - physiopathology, Follow-Up Studies
Male, Aluminum Compounds - therapeutic use, Bicuspid - pathology, 610, Tooth Apex - physiopathology, Minocycline, Minocycline - administration & dosage, Root Canal Therapy - methods, Odontogenesis - physiology, Physiologic - physiology, Silicates - therapeutic use, Anti-Infective Agents, Ciprofloxacin, Metronidazole, Calcium Compounds - therapeutic use, Anti-Bacterial Agents - administration & dosage, Dental Pulp Necrosis, Humans, Bicuspid, Aluminum Compounds, Child, Blood Coagulation, Neovascularization, Anti-Infective Agents - administration & dosage, Incisor - pathology, Dental Pulp, Blood Coagulation - physiology, Dental Pulp Necrosis - therapy, Guided Tissue Regeneration, Oxides - therapeutic use, Periapical Periodontitis - therapy, Root Canal Preparation - methods, Calcium Compounds, Root Canal Filling Materials - therapeutic use, Anti-Bacterial Agents, Guided Tissue Regeneration - methods, Incisor, Drug Combinations, Treatment Outcome, Ciprofloxacin - administration & dosage, Neovascularization, Physiologic - physiology, Female, Metronidazole - administration & dosage, Dental Pulp Cavity, Dental Pulp Cavity - blood supply, Dental Pulp - blood supply - physiopathology, Follow-Up Studies
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