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Cerebral phaeohyphomycosis mimics high-grade astrocytoma

Name: Cerebral phaeohyphomycosis mimics high-grade astrocytoma
Keywords: Adult, Male, Antifungal Agents, Brain Neoplasms, Fungi, Hyphae, Brain, Brain Abscess, Astrocytoma, Prognosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2008Publisher:Elsevier BVJournal:Journal of Clinical Neuroscience, volume 15, pages 1,061-1,066 (issn: 0967-5868,

Authors: Haring J.W. Nauta; Erik F. Hauck; Erik F. Hauck; Michael R. McGinnis;

doi: 10.1016/j.jocn.2007.08.019

pmid: 18614370

Cerebral phaeohyphomycosis mimics high-grade astrocytoma

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Abstract

The incidence of cerebral phaeohyphomycosis, an infection caused by a dark-pigmented fungus, is increasing. The infection may mimic a high-grade glioma clinically and radiographically. Magnetic resonance spectroscopy may be helpful in differentiating the two. We report two cases to increase the awareness of cerebral phaeohyphomycosis in the clinical neurosciences. Early biopsy establishing the diagnosis, followed by aggressive combined surgical and medical management is necessary for a good outcome.

Related Organizations

The University of Texas Medical Branch at Galveston
United States
The University of Texas Southwestern Medical Center
United States

Keywords

Adult, Male, Antifungal Agents, Brain Neoplasms, Fungi, Hyphae, Brain, Brain Abscess, Astrocytoma, Prognosis, Magnetic Resonance Imaging, Neurosurgical Procedures, Diagnosis, Differential, Fatal Outcome, Central Nervous System Fungal Infections, Debridement, Disease Progression, Humans, Female, Aged

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	16
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average