Volcanic ashes from the Puna and surrounding Andean areas in northern Argentina show that sometimes volcanic ash deposits are very well preserved (up to several million years) and can remain a potential hazard for the environment in a similar way as current deposits. Eight ashes have been characterized by SEM-EDX and DRX, and their potential released geochemical fluxes were examined by using water and nitric acid batches, which are analyzed by ICP-OES, ICP-MS and ISE (F). Results demonstrate that water batch system is better medium than nitric acid for this study. The high and fast reactivity of these ancient ashes is mainly associated with their high content in glass. The order of magnitude of released contents of implied elements is consistent among the samples, i.e., Al>B>Fe>Zn>F>P>Mn>Ba>Sr>Li>Ti>Rb>Cu>Ni>Sb>Pb>As>Cr>V. Ash-water interaction, although infrequent in arid regions such as the Puna Region in northern Argentina, introduces rapid changes in the geochemical fluxes of elements and pH and may constitute a potential hazard for the environment. In fact, many of these elements are included in the drinking water guidelines due to their potential toxicity and may constitute potential hazards for the environment and human health.