
pmid: 20688472
To present some simple graphical and quantitative ways to assist interpretation and improve presentation of results from multiple-treatment meta-analysis (MTM).We reanalyze a published network of trials comparing various antiplatelet interventions regarding the incidence of serious vascular events using Bayesian approaches for random effects MTM, and we explore the advantages and drawbacks of various traditional and new forms of quantitative displays and graphical presentations of results.We present the results under various forms, conventionally based on the mean of the distribution of the effect sizes; based on predictions; based on ranking probabilities; and finally, based on probabilities to be within an acceptable range from a reference. We show how to obtain and present results on ranking of all treatments and how to appraise the overall ranks.Bayesian methodology offers a multitude of ways to present results from MTM models, as it enables a natural and easy estimation of all measures based on probabilities, ranks, or predictions.
Clinical Trials as Topic, Models, Statistical, Platelet Aggregation Inhibitors/therapeutic use, Bayes Theorem, *Bayes Theorem, Clinical Trials as Topic/*statistics & numerical data, Stroke, Meta-Analysis as Topic, Ischemic Attack, Transient, Data Interpretation, Statistical, *Meta-Analysis as Topic, Data Display, Humans, Ischemic Attack, Transient/drug therapy, Stroke/drug therapy, Platelet Aggregation Inhibitors
Clinical Trials as Topic, Models, Statistical, Platelet Aggregation Inhibitors/therapeutic use, Bayes Theorem, *Bayes Theorem, Clinical Trials as Topic/*statistics & numerical data, Stroke, Meta-Analysis as Topic, Ischemic Attack, Transient, Data Interpretation, Statistical, *Meta-Analysis as Topic, Data Display, Humans, Ischemic Attack, Transient/drug therapy, Stroke/drug therapy, Platelet Aggregation Inhibitors
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