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</script>pmid: 36028008
A 66-year-old man with age-related macular degeneration was admitted for new left cerebellar and right parietal hemorrhagic tumours. Excisional biopsy of the left cerebellar lesion demonstrated primary CNS lymphoma (PCNSL) of diffuse large B-cell morphology. No intraocular inflammation was present. Fundus examination revealed numerous drusen at the posterior pole of the left eye only, confirmed as sub–retinal pigment epithelium (sub-RPE) deposits on optical coherence tomography. Complete resolution of these unilateral sub-RPE drusenoid deposits occurred with systemic treatment for PCNSL alone using methotrexate, cytarabine, thioepta, and rituximab (MATRix) chemotherapy. No diagnostic vitrectomy was needed. In this photo essay we illustrate the spontaneous resolution of sub-RPE drusenoid deposits with systemic chemotherapy.
Optic Disk Drusen, Humans, Retinal Drusen, Retina
Optic Disk Drusen, Humans, Retinal Drusen, Retina
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