Fecal elastase-1: Utility in pancreatic function in cystic fibrosis
Copyright policy )Fecal elastase-1: Utility in pancreatic function in cystic fibrosis
Early detection and management of pancreatic insufficiency is essential to optimize health and outcomes in cystic fibrosis patients. The gold standard measures for assessment of pancreatic function are direct pancreatic stimulation tests, which have numerous limitations. Estimation of fecal elastase-1 level to determine pancreatic function is an attractive alternative as the test is simple, rapid, cost-effective and easy to perform even in children. This review summarizes the data from studies reflecting the validity, limitation and advantages of fecal elastase-1 in assessing pancreatic function in cystic fibrosis patients.
- Cincinnati Children's Hospital Medical Center United States
Pulmonary and Respiratory Medicine, Cystic Fibrosis, Pancreatic Elastase, Cystic elastase fecal fibrosis, Reproducibility of Results, Enzyme-Linked Immunosorbent Assay, Clinical Enzyme Tests, Sensitivity and Specificity, Feces, Humans, Exocrine Pancreatic Insufficiency, Pediatrics, Perinatology, and Child Health, Carrier Proteins, Biomarkers
Pulmonary and Respiratory Medicine, Cystic Fibrosis, Pancreatic Elastase, Cystic elastase fecal fibrosis, Reproducibility of Results, Enzyme-Linked Immunosorbent Assay, Clinical Enzyme Tests, Sensitivity and Specificity, Feces, Humans, Exocrine Pancreatic Insufficiency, Pediatrics, Perinatology, and Child Health, Carrier Proteins, Biomarkers
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