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A fatal complication of tirofiban in an octogenarian: Diffuse alveolar hemorrhage

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2010Publisher:Elsevier BVJournal:Journal of Cardiology Cases, volume 2, pages e48-e51 (issn: 1878-5409,

Authors: Hakan Hasdemir; Nihat Özer; Özer Soylu; Mehmet Ergelen; Tolga Sinan Güvenç; Özge Güzelburç; Servet Altay; +1 Authors

doi: 10.1016/j.jccase.2010.02.002

pmid: 30532804

pmc: PMC6265041

A fatal complication of tirofiban in an octogenarian: Diffuse alveolar hemorrhage

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Abstract

An 84-year-old female patient with a past medical history significant for hypertension and diabetes mellitus, was admitted to the Emergency Department with acute coronary syndrome and complete atrioventricular block. She underwent a successful primary percutaneous coronary intervention. Ten minutes following tirofiban administration, the patient complained of hemoptysis and severe dyspnea. After chest X-ray and diagnostic bronchoscopy, she was diagnosed with diffuse alveolar hemorrhage. She died because of respiratory insufficiency on the third day of hospitalization. We present the first tirofiban-related diffuse alveolar hemorrhage case caused with half of the recommended dose of tirofiban used in the setting of non-ST-elevation myocardial infarction.

Keywords

Tirofiban, Diffuse alveolar hemorrhage, Glycoprotein IIb/IIIa antagonist, Acute coronary syndrome, Cardiology and Cardiovascular Medicine

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