Toll-like receptors and atopy

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2005 English Publisher:Elsevier BVJournal:Journal of Allergy and Clinical Immunology, volume 116, pages 467-470 (issn: 0091-6749,

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Authors: Pierre Olivier, Fiset; Meri Katarina, Tulic; Qutayba, Hamid;

doi: 10.1016/j.jaci.2005.04.034

pmid: 16083812

Toll-like receptors and atopy

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Abstract

The Toll-like receptors (TLRs) are a recently discovered family of receptors involved in the innate recognition of pathogens. TLRs have much homology to the IL-1 receptor family and the Drosophila Toll protein, and at least 10 distinct TLRs have now been identified in human subjects (Fig 1). TLR ligands are highly conserved structures and molecules present on many pathogens, the so-called pathogen-associated

Related Organizations

McGill University
Canada

Keywords

Lipopolysaccharides, Membrane Glycoproteins, Toll-Like Receptors, Hypersensitivity, Cytokines, Humans, Receptors, Cell Surface

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