Sifting through CD8 + T Cell Memory

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2016 English Publisher:Elsevier BVJournal:Immunity, volume 45, pages 1,184-1,186 (issn: 1074-7613,

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Authors: Matthew D, Martin; Vladimir P, Badovinac;

doi: 10.1016/j.immuni.2016.12.005

pmid: 28002725

Sifting through CD8 + T Cell Memory

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Abstract

In this issue of Immunity, Gerlach et al. (2016) describe three distinct memory CD8+ T cell subsets based upon expression of the fractalkine receptor CX3CR1. Their findings revise the paradigm of effector and central memory T cells by revealing a subset of CD8+ memory T cells defined by intermediate levels of expression of CX3CR1 that conducts tissue surveillance.

Related Organizations

University of Iowa
United States

Keywords

T-Lymphocyte Subsets, CD8-Positive T-Lymphocytes, Immunologic Memory

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