
pmid: 19538926
Mutations in the human NLRP3 gene cause interleukin-1beta-related autoinflammatory syndromes. In this issue of Immunity, Brydges et al. (2009) and Meng et al. (2009) report the characterization of Nlrp3 gene-targeted mice harboring mutations mimicking those causing disease in humans.
Inflammation, Mice, Infectious Diseases, Immunology, Interleukin-1beta, NLR Family, Pyrin Domain-Containing 3 Protein, Immunology and Allergy, Animals, Gene Knock-In Techniques, T-Lymphocytes, Helper-Inducer, Carrier Proteins
Inflammation, Mice, Infectious Diseases, Immunology, Interleukin-1beta, NLR Family, Pyrin Domain-Containing 3 Protein, Immunology and Allergy, Animals, Gene Knock-In Techniques, T-Lymphocytes, Helper-Inducer, Carrier Proteins
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