Aging and Innate Immunity

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2006 English Publisher:Elsevier BVJournal:Immunity, volume 24, pages 491-494 (issn: 1074-7613,

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Authors: Solana, Rafael; Pawelec, Graham; Tarazona, Raquel;

doi: 10.1016/j.immuni.2006.05.003

pmid: 16713963

Aging and Innate Immunity

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Abstract

Adaptive immunity undergoes severe deterioration with age and represents the main problem in the elderly. However, evidence accumulated over the last decade supports the hypothesis that aging also has a profound impact on innate immunity, which in turn markedly impacts the health and longevity of older people.

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Keywords

Aging, Infectious Diseases, Immunology, Immunology and Allergy, Humans, Immunity, Innate, Signal Transduction

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