CD14: Chaperone or Matchmaker?

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2006 English Publisher:Elsevier BVJournal:Immunity, volume 24, pages 127-129 (issn: 1074-7613,

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Authors: Finberg, Robert W.; Kurt-Jones, Evelyn A.;

doi: 10.1016/j.immuni.2006.01.010

pmid: 16473824

CD14: Chaperone or Matchmaker?

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Abstract

In this issue of Immunity, describe a physical and functional relationship between Toll-like receptor 3 (TLR3) and the pattern recognition protein CD14. In the presence of CD14, TLR3-mediated signal transduction events are amplified.

Related Organizations

University of Massachusetts Medical School
United States

Keywords

Immunology, Cytoplasmic Vesicles, Lipopolysaccharide Receptors, Toll-Like Receptor 3, Mice, Infectious Diseases, Immunology and Allergy, Animals, Humans, Adaptor Proteins, Signal Transducing, Molecular Chaperones, Signal Transduction

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