descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2014 English Publisher:Elsevier BVJournal:Immunology Letters, volume 162, pages 95-102 (issn: 0165-2478,

Authors: Koenderman, L.; Buurman, W.; Daha, M.R.;

doi: 10.1016/j.imlet.2014.10.010

pmid: 25455595

handle: 1887/105342

The innate immune response

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Abstract

The innate immune response is of prime importance in the immediate recognition and elimination of invading micro-organisms. However, deregulation of this system is clearly associated with the pathogenesis of a wide range of inflammatory diseases. Innate immunity consists of a humoral and a cellular branch, which are closely interacting. An additional level of control is found at the level of neuronal reflexes that can fine-tune these immunological mechanisms.

Related Organizations

Maastricht University
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Leiden University Medical Center
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Maastricht University Medical Centre
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Utrecht University
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University Medical Center Utrecht
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Keywords

Innate immune response, Inflammation, Complement system, Macrophages, Neuronal regulation, Immunity, Innate, Animals, Humans, Cellular and humoral branch, Granulocytes

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