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Looking back on the alternative complement pathway

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2018Embargo end date: 30 Apr 2019 United Kingdom English Publisher:Elsevier BVJournal:Immunobiology, volume 223, pages 519-523 (issn: 0171-2985, Copyright policy )
Authors: Lachmann, Peter J;

doi: 10.1016/j.imbio.2018.02.001 , 10.17863/cam.39281

pmid: 29525356

Looking back on the alternative complement pathway

Abstract

The alternative pathway of complement originated from the Properdin pathway originally described by the Pillemer laboratory in the 1950s. This work generated great controversy and it took several decades for a consensus on its components, its reaction sequence and its functions to emerge. This paper reviews this history and attempts to clarify some of the ambiguities that remain.

Country
United Kingdom
Related Organizations
Keywords

Properdin, Alternative pathway, Complement Pathway, Alternative, Complement, Animals, Humans, History, 20th Century, History, 21st Century

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 35
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
35
Top 10%
Average
Top 10%
Green
gold