
pmid: 16781716
Secondary amenorrhea has always been a challenge for the gynecologist. The incidence is reported to be between 1.4% and 3% in the general population [1,2], and its causes can be hypothalamic (62%), pituitary (15%), ovarian (12%), or anatomical (7%). Intrauterine devices have been used to treat Asherman syndrome. Lately, copper intrauterine devices have been proposed to treat secondary amenorrhea [3]. As in the treatment of Asherman syndrome, their effect is probably related to the release of prostaglandins in the endometrium. Prostaglandins affect homeostasis through their effect on vascular tone and platelet aggregation, and thus lead to an increased blood flow [3]. This preliminary study was carried out to evaluate
Adult, Treatment Outcome, Humans, Female, Intrauterine Devices, Copper, Amenorrhea, Hypothalamic Diseases
Adult, Treatment Outcome, Humans, Female, Intrauterine Devices, Copper, Amenorrhea, Hypothalamic Diseases
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