IS THERE AN ASSOCIATION BETWEEN PULMONARY EMBOLISM AND THE USE OF PEG-ASPARAGINASE IN CHILDREN WITH LEUKEMIA?

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2023 English Publisher:Elsevier BVJournal:Hematology, Transfusion and Cell Therapy, volume 45, pages S43-S44 (issn: 2531-1379,

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Authors: Emine Yılmaz Orulluoğlu; Zühre Kaya; Merve Yazol; Büşra Topuz Turkcan; Serap Kirkiz Kayalı; Ülker Koçak;

doi: 10.1016/j.htct.2023.09.077

IS THERE AN ASSOCIATION BETWEEN PULMONARY EMBOLISM AND THE USE OF PEG-ASPARAGINASE IN CHILDREN WITH LEUKEMIA?

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Abstract

We present two leukemic children who developed pulmonary thromboembolism (PTE) after using PEG-asparaginase.The first child, an eight-year-old boy, was diagnosed with T-acute lymphoblastic leukemia (ALL). The second child, a 6-year-old boy, was diagnosed with B-ALL.They developed PTE following induction phases of BFM protocol's.They were given PEG-asparaginase at a dose of 2500IU/m2. Heparin was succesfully used in both cases.Physician may consider prophylactic anticoagulants during induction.

Related Organizations

Gazi University
Turkey

Keywords

Diseases of the blood and blood-forming organs, RC633-647.5

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