Genetics of Takotsubo Syndrome
Copyright policy )Genetics of Takotsubo Syndrome
Takotsubo syndrome (TTS) is an enigmatic disease with a multifactorial and still unresolved pathogenesis. A genetic predisposition has been suggested based on the few familial TTS cases. Conflicting results have been published regarding the role of functional polymorphisms in relevant candidate genes, such as α1-, β1-, and β2-adrenergic receptors; G protein-coupled receptor kinase 5; and estrogen receptors. Further research is required to help clarify the role of genetic susceptibility in TTS.
G-Protein-Coupled Receptor Kinase 5, Adrenoceptor polymorphisms; Catecholamine-induced myocardial toxicity; Takotsubo syndrome;, Polymorphism, Genetic, Takotsubo Cardiomyopathy, Receptors, Adrenergic, alpha-1, Humans, Genetic Predisposition to Disease, Receptors, Adrenergic, beta-2, Receptors, Adrenergic, beta-1
G-Protein-Coupled Receptor Kinase 5, Adrenoceptor polymorphisms; Catecholamine-induced myocardial toxicity; Takotsubo syndrome;, Polymorphism, Genetic, Takotsubo Cardiomyopathy, Receptors, Adrenergic, alpha-1, Humans, Genetic Predisposition to Disease, Receptors, Adrenergic, beta-2, Receptors, Adrenergic, beta-1
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