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Amino acid sequence of the Felis catus prion protein

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2004 English Publisher:Elsevier BVJournal:Gene, volume 341, pages 249-253 (issn: 0378-1119,

Authors: Dominikus A. Lysek; Kurt Wüthrich; Lucas G. Nivón;

doi: 10.1016/j.gene.2004.07.002

pmid: 15474307

Amino acid sequence of the Felis catus prion protein

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Abstract

A new determination of the house cat (Felis catus) prion protein gene sequence (fPrnp), which has so far been subject of controversy, is reported. The newly determined fPrnp sequence is similar to dog (Canis familiaris) and mink (Mustela putorius) Prnp, but differs significantly from both fPrnp sequences that were previously deposited in the GenBank. Comparison of the canine and feline prion protein sequences suggests a set of amino acid replacements relative to bovine PrP that might relate to the observed different susceptibilities of the two species to TSE infection by ingestion of BSE-infected beef.

Related Organizations

ETH Zurich
Switzerland
Institute of Molecular Biology and Biophysics
Switzerland

Keywords

Base Sequence, Sequence Homology, Amino Acid, Prions, Molecular Sequence Data, DNA, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid, Cats, Animals, Amino Acid Sequence, Sequence Alignment

3 Research products, page 1 of 1

Felis catus (domestic cat) partial prion protein
2018IsRelatedTo
Felis catus prion protein (PRP) gene, partial cds.
2018IsRelatedTo
Major prion protein
2017IsRelatedTo

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