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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Current Opinion in G...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Current Opinion in Genetics & Development
Article . 2006 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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The social lives of migrating cells in Drosophila

Authors: Denise J, Montell;

The social lives of migrating cells in Drosophila

Abstract

Studies of cell migration in Drosophila are yielding insights into the complex interactions migrating cells have with each other and with the cells in their environment. Intriguing links between factors that promote cell migration and those that control cell survival have been reported recently. For example, migrating germ cells compete with the surrounding somatic tissue for the substrate of the lipid phosphate phosphatases encoded by the genes Wunen and Wunen2. Germ cells take up the dephosphorylated lipid and require it for their survival. In addition, the secreted growth factors called PVFs, previously thought to guide the migrations of hemocytes in the embryo, were found to function instead predominantly as survival factors. And in border cells, DIAP1 and Dronc, two proteins known mainly for their ability to regulate cell death, were found to control cell migration.

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Keywords

Hemocytes, Cell Survival, Phosphatidate Phosphatase, Membrane Proteins, Lipids, Salivary Glands, Mesoderm, Germ Cells, Cell Movement, Animals, Drosophila Proteins, Drosophila

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
58
Top 10%
Top 10%
Top 10%
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