Expression of E26 transformation specific (ETS-1) related to angiogenesis in ovarian endometriosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2004 English Publisher:Elsevier BVJournal:Fertility and Sterility, volume 82, pages 507-510 (issn: 0015-0282,

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Authors: Hideki, Sakaguchi; Jiro, Fujimoto; Ikumi, Aoki; Hiroshi, Toyoki; Eriko, Sato; Teruhiko, Tamaya;

doi: 10.1016/j.fertnstert.2004.02.103

pmid: 15302318

Expression of E26 transformation specific (ETS-1) related to angiogenesis in ovarian endometriosis

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Abstract

ETS-1 in ovarian endometriomas was significantly positively correlated with microvessel counts (MVCs), but ETS-1 and MVC were not significantly altered during the menstrual cycle. Because ETS-1 persistently expresses in the subepithelial area of endometriotic endometrium, this might contribute to the growth of ovarian endometriomas via subepithelial angiogenesis independently of the menstrual cycle.

Related Organizations

Gifu University
Japan

Keywords

Adult, Factor VIII, Neovascularization, Pathologic, Proto-Oncogene Proteins c-ets, Microcirculation, Endometriosis, Immunohistochemistry, Proto-Oncogene Protein c-ets-1, Gene Expression Regulation, Reference Values, Proto-Oncogene Proteins, Humans, Female, Ovarian Diseases, Transcription Factors

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