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FEBS Letters
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FEBS Letters
Article . 2010 . Peer-reviewed
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FEBS Letters
Article . 2010
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A novel Aspergillus oryzae esterase that hydrolyzes 4‐hydroxybenzoic acid esters

Authors: Koseki, Takuya; Mihara, Koji; Murayama, Tetsuya; Shiono, Yoshihito;

A novel Aspergillus oryzae esterase that hydrolyzes 4‐hydroxybenzoic acid esters

Abstract

In this study we report the biochemical characterization of a hypothetical protein from Aspergillus oryzae exhibiting sequence identity with feruloyl esterase and tannase from the genus Aspergillus. The purified recombinant protein showed a hydrolytic activity toward the ethyl, propyl, or butyl esters of 4‐hydroxybenzoic acid, but did not show feruloyl esterase or tannase activity. Finally, the enzyme decreased the antimicrobial activity of parabens against A. oryzae via hydrolysis of the ester bond present in butyl 4‐hydroxybenzoic acid.

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Keywords

4-Hydroxybenzoic acid ester, Antifungal Agents, Aspergillus oryzae, Hydrolysis, Molecular Sequence Data, Parabens, Esters, Esterase, Recombinant Proteins, Amino Acid Sequence, Paraben, Carboxylic Ester Hydrolases, Phylogeny

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    popularity
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    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
34
Top 10%
Top 10%
Top 10%
bronze