Bone Marrow Aspirate Concentrate for Bone Healing in Foot and Ankle Surgery

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2016 English Publisher:Elsevier BVJournal:Foot and Ankle Clinics, volume 21, pages 839-845 (issn: 1083-7515,

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Authors: Joshua S, Harford; Travis J, Dekker; Samuel B, Adams;

doi: 10.1016/j.fcl.2016.07.005

pmid: 27871416

Bone Marrow Aspirate Concentrate for Bone Healing in Foot and Ankle Surgery

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Abstract

Autologous bone marrow aspirate concentrate (BMAC) has become a popular orthobiologic to augment bone healing. The potential benefit comes from osteoprogenitor cells and growth factors that can lead to new bone formation in the setting of foot and ankle arthrodesis procedures. BMAC has an excellent safety record and has demonstrated efficacy in animal models of bone healing. Although scant, the literature on the use of BMAC in foot and ankle surgery does demonstrate promise for this orthobiologic adjuvant.

Related Organizations

Duke University
United States
Duke Medical Center
United States

Keywords

Fracture Healing, Wound Healing, Foot, Arthrodesis, Bone Marrow Cells, Bone Marrow, Animals, Humans, Intercellular Signaling Peptides and Proteins, Ankle, Bone Marrow Transplantation

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