Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle
Copyright policy )Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle
Plasmodium yoelii is a rodent parasite commonly used as a model to study malaria infection. It is the preferred model parasite for liver-stage immunological studies and is also widely used to study hepatocyte, erythrocyte and mosquito infection. We have generated a P. yoelii yoelii 17XNL line that is stably transfected with the green fluorescent protein (gfp) gene. This parasite line constitutively expresses high levels of GFP during the complete parasite life cycle including liver, blood and mosquito stages. These fluorescent parasites can be used in combination with fluorescence activated cell sorting or live microscopy for a wide range of experimental applications.
- National Defense Medical College Japan
- New York University United States
Life Cycle Stages, Erythrocytes, Green Fluorescent Proteins, Drug Resistance, Gene Expression Regulation, Developmental, Plasmodium yoelii, Flow Cytometry, Transfection, Insect Vectors, Malaria, Antimalarials, Disease Models, Animal, Mice, Pyrimethamine, Liver, Anopheles, Animals
Life Cycle Stages, Erythrocytes, Green Fluorescent Proteins, Drug Resistance, Gene Expression Regulation, Developmental, Plasmodium yoelii, Flow Cytometry, Transfection, Insect Vectors, Malaria, Antimalarials, Disease Models, Animal, Mice, Pyrimethamine, Liver, Anopheles, Animals
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