
The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.
Extracellular Matrix Proteins, Cell Membrane Permeability, Eye Diseases, Organogenesis, Lens Capsule, Crystalline, Accommodation, Ocular, Basement Membrane, Biomechanical Phenomena, Extracellular Matrix, Pregnancy, Animals, Humans, Female, Signal Transduction
Extracellular Matrix Proteins, Cell Membrane Permeability, Eye Diseases, Organogenesis, Lens Capsule, Crystalline, Accommodation, Ocular, Basement Membrane, Biomechanical Phenomena, Extracellular Matrix, Pregnancy, Animals, Humans, Female, Signal Transduction
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 260 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 1% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 1% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
