Peroxisomes and peroxisomal disorders: The main facts
Copyright policy )Peroxisomes and peroxisomal disorders: The main facts
The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable. This review examines the most important aspects concerning peroxisomes (i.e. peroxisome proliferation, peroxisome biogenesis, metabolic functions of mammalian peroxisomes) and presents the most significant trends and advances in the study of peroxisomal disorders.
- Roma Tre University Italy
- Sapienza University of Rome Italy
Fatty Acids, Membrane Proteins, Peroxisomal Β-oxidation; Peroxisomal biogenesis; Peroxisomal disorders; Peroxisomal metabolism; Peroxisomes, Bile Acids and Salts, Peroxisomal Disorders, Oxidative Stress, Protein Transport, Cholesterol, Peroxisomes, Humans, Oxidation-Reduction, Cell Proliferation
Fatty Acids, Membrane Proteins, Peroxisomal Β-oxidation; Peroxisomal biogenesis; Peroxisomal disorders; Peroxisomal metabolism; Peroxisomes, Bile Acids and Salts, Peroxisomal Disorders, Oxidative Stress, Protein Transport, Cholesterol, Peroxisomes, Humans, Oxidation-Reduction, Cell Proliferation
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