A new model for the environmental assessment of environmental technologies, EASETECH, has been developed. The primary aim of EASETECH is to perform life-cycle assessment (LCA) of complex systems handling heterogeneous material flows. The objectives of this paper are to describe the EASETECH framework and the calculation structure. The main novelties compared to other LCA software are as follows. First, the focus is put on material flow modelling, as each flow is characterised as a mix of material fractions with different properties and flow compositions are computed as a basis for the LCA calculations. Second, the tool has been designed to allow for the easy set-up of scenarios by using a toolbox, the processes within which can handle heterogeneous material flows in different ways and have different emission calculations. Finally, tools for uncertainty analysis are provided, enabling the user to parameterise systems fully and propagate probability distributions through Monte Carlo analysis.