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Archivio istituzionale della ricerca - Università di Ferrara
Article . 2016
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European Journal of Pharmaceutics and Biopharmaceutics
Article . 2016 . Peer-reviewed
License: Elsevier TDM
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https://pubmed.ncbi.nlm.nih.go...
Article . 2016
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https://dx.doi.org/10.1016/j.e...
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Encapsulation of cannabinoid drugs in nanostructured lipid carriers

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2016 Italy English Publisher:Elsevier BVJournal:European Journal of Pharmaceutics and Biopharmaceutics, volume 102, pages 87-91 (issn: 0939-6411, Copyright policy )
Authors: ESPOSITO, Elisabetta; Drechsler, Markus; CORTESI, Rita; NASTRUZZI, Claudio;

doi: 10.1016/j.ejpb.2016.03.005

pmid: 26952905

handle: 11392/2355421

Encapsulation of cannabinoid drugs in nanostructured lipid carriers

Abstract

This study describes the development and optimization of a method to encapsulate the potent and expensive cannabinoids drugs in nanostructured lipid carriers; namely, URB597, AM251 and rimonabant have been considered. NLC production by melt and ultrasonication protocol has been specifically designed to optimize nanoparticle recovery and drug encapsulation efficiency. Special care has been devoted to the modality of oil and water phase emulsification and the entire production has been studied and discussed. NLC recovery, morphology, dimensional distribution and encapsulation efficiency are presented.

Country
Italy
Related Organizations
Keywords

Nanostructured lipid carriers, Cannabinoid drugs, Cryo-TEM, nanoparticles, rimonabant, delivery, receptor, Drug Carriers, Piperidines, Cannabinoids, Benzamides, Pyrazoles, Carbamates, Rimonabant, Lipids, Nanostructures

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 49
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
49
Top 10%
Top 10%
Top 10%
Green