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Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2022Publisher:Elsevier BVJournal:European Journal of Medicinal Chemistry Reports, volume 6, page 100,066 (issn: 2772-4174,

Authors: Ramveer Singh; Narashans Alok Sagar; Navneet Kumar;

doi: 10.1016/j.ejmcr.2022.100066

Bio-inspired green fabrication of silver nanoparticles (AgNPs) using aqueous leaves extract of Ipomoea carnea Jacq. To tackle multiple drug resistance MTCC bacterial strains

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Abstract

AgNPs are employed in several applications, and we used Ipomoea carnea aqueous leaves extract to enhance the metal nanoparticle synthesis process. This study suggested that aqueous extract from I. carnea leaves can reduce silver nitrate (AgNO3) and act as a stabilizing and capping agent. The specific Plasmon resonance (SPR) was found between 390-410 nm in a UV–Vis spectrophotometer. Field Emission Scanning Electron Microscope (FE-SEM) and X-ray diffraction (XRD) analysis confirm the size between 11.21-46.90 nm with spherical face-center-cubic (FCC) crystals. Additionally, the antibacterial activity of synthesized AgNPs was also evaluated against four standard bacterial pathogens i.e. Klebsiella pneumoniae (MTCC 432), Staphylococcus aureus (MTCC 1144), Streptococcus pneumoniae (MTCC 655), and Pseudomonas aeruginosa (MTCC 2474) and Brine shrimp lethality assay (BSLA) was used to check the toxicity. Synthesized AgNPs were found significantly effective against all MTCC strains with a 1359.03 ng/mL LC50 value.

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Keywords

Ipomoea carnea, Green synthesis, AgNPs, RS1-441, Other systems of medicine, Pharmacy and materia medica, EDX, Antimicrobial, FE-SEM, RZ201-999

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