To define the degree of heart derangement in recent myocardial infarction (MI) occurring in different wall locations of myocardium, we echocardiographically evaluated left ventricular volumes, ejection fraction, wall-motion score index, isovolumetric contraction and relaxation time, ejection time, and index of myocardial performance in 74 patients with MI. Participants were chosen among the patients with MI of comparable extent and interesting unlike zones of myocardial walls. Mean values of evaluated left ventricular end-diastolic and end-systolic volumes and ejection fraction were nearly alike in all patients, whereas wall-motion score index and index of myocardial performance were cleary prolonged in those with anterior MI in comparison with the values recorded in patients with lateral or inferior MI. The mean values of isovolumetric contraction and relaxation time suggest that a prevalent systolic dysfunction is present in the early phase of MI. In addition, the different index of myocardial performance prolongation in MI otherwise located suggests evidence that MI located in the anterior wall has more serious effect than lateral or inferior MI.