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Glycosylation, diabetes and dengue: Effect on severity?

Name: Glycosylation, diabetes and dengue: Effect on severity?
Creator: Viroj Wiwanitkit
Keywords: Dengue, Diabetes Complications, 0301 basic medicine, 03 medical and health sciences, Glycosylation, 0302 clinical medicine, Molecular Mimicry, Integrin beta3, Computational Biology, Humans

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2011Publisher:Elsevier BVJournal:Diabetes & Metabolic Syndrome: Clinical Research & Reviews, volume 5, pages 158-159 (issn: 1871-4021,

Authors: Viroj Wiwanitkit;

doi: 10.1016/j.dsx.2012.02.006

pmid: 22813570

Glycosylation, diabetes and dengue: Effect on severity?

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Abstract

Co-presentation between dengue and diabetes mellitus (DM) can be expected. The author hereby assesses the effect of glycosylation process in poor glycemic control cases on the course of dengue infection.The aim of this work is to assess the effect of glycosylation of CD61 on the pathogenesis of dengue hemorrhagic fever. The hypothetical bioinformatics approach is used in this research.Significant change of similarity between CD61 and dengue NS1 after glycosylation can be detected.These findings might imply that immunomimicking process should be more difficult to occur.

Keywords

Dengue, Diabetes Complications, Glycosylation, Molecular Mimicry, Integrin beta3, Computational Biology, Humans, Comorbidity

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